Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.51 |
| ▸ | WNT3A | P56704 | 5/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15749928 | 0.84 | DYRK1A (0.60) | DYRK1AERN1GSK3BPTGES2KCNH2 | |
| SCHEMBL19724359 | 0.83 | RIPK1 (0.53) | DYRK1ACTNNB1WNT3ANOTUMRIPK1 | |
| SCHEMBL8185847 | 0.82 | NOTUM (0.47) | DYRK1ACTNNB1WNT3ANOTUMRIPK1 | |
| SCHEMBL28137011 | 0.81 | KCNH2 (0.52) | DYRK1ACTNNB1WNT3ANOTUMRIPK1 | |
| SCHEMBL27578676 | 0.79 | ERN1 (0.50) | DYRK1ACTNNB1WNT3ANOTUMRIPK1 | |
| SCHEMBL19188065 | 0.79 | NOTUM (0.50) | DYRK1ACTNNB1WNT3ANOTUMRIPK1 | |
| SCHEMBL16574214 | 0.79 | NOTUM (0.50) | DYRK1ACTNNB1WNT3ANOTUMRIPK1 | |
| Biphenyl SCHEMBL27589817 | 0.78 | CTNNB1 (0.45) | DYRK1ACTNNB1WNT3ANOTUMRIPK1 | |
| SCHEMBL17610580 | 0.78 | NOTUM (0.49) | DYRK1ACTNNB1WNT3ANOTUMRIPK1 | |
| SCHEMBL27578678 | 0.78 | CTNNB1 (0.47) | DYRK1ACTNNB1WNT3ANOTUMRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148937-A1 | INHIBITING HYDROCARBON HYDRATE AGGLOMERATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148937-A1 | INHIBITING HYDROCARBON HYDRATE AGGLOMERATION | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AHR, SHH | DYRK1A 4549/4885CTNNB1 156/4885WNT3A 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.