Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999184 | 0.93 | DDR1 (0.37) | MAPK14DDR1HPGDSSCN9ASCN7A | |
| SCHEMBL21999183 | 0.92 | MAPK14 (0.34) | MAPK14HPGDSHPGDSCN9ASCN7A | |
| SCHEMBL21998965 | 0.89 | DDR1 (0.35) | DDR1RORCSCN9A | |
| SCHEMBL21796211 | 0.88 | DDR1 (0.38) | DDR1CNR1CNR2RORC | |
| SCHEMBL21998968 | 0.87 | DDR1 (0.30) | DDR1CNR2 | |
| SCHEMBL21796209 | 0.85 | DDR1 (0.31) | DDR1CNR2RORC | |
| SCHEMBL29774756 | 0.85 | DDR1 (0.31) | DDR1CNR2RORC | |
| SCHEMBL21999189 | 0.85 | F10 (0.36) | MAPK14HPGDSSCN9ASCN7AKCNH2 | |
| SCHEMBL31003479 | 0.85 | HPGDS (0.37) | HPGDSTTKRIPK2 | |
| SCHEMBL21998969 | 0.84 | CNR2 (0.31) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11089783-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-17 | — | — | US | disclosed |
| US-20200146293-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11089783-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | AHR, DDT, CYP8B1 | MAPK14 3819/4885DDR1 2201/4885HPGDS 647/4885 |
| US-20200146293-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | AHR, DDT, CYP8B1 | MAPK14 3819/4885DDR1 2201/4885HPGDS 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.