SCHEMBL21999243

SCHEMBL21999243

CC(C)(C)OC(=O)N(C[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1)c1ccon1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 0.57
MAOA P21397 6/20 0.55
PTGS1 P23219 2/20 0.55
SDHA P31040 2/20 0.55
LMNA P02545 1/20 0.55
CALML3 P27482 1/20 0.55
F10 P00742 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20333808 0.92 MAOA (0.48) MAOBMAOAPTGS1SDHALMNA
SCHEMBL30817024 0.90 MAOB (0.48) MAOBMAOAPTGS1SDHALMNA
SCHEMBL18410808 0.90 MAOB (0.45) MAOBMAOAPTGS1SDHALMNA
SCHEMBL13298877 0.89 MAOA (0.47) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6765964 0.89 MAOB (0.55) MAOBMAOAPTGS1SDHALMNA
SCHEMBL3325808 0.87 MAOB (0.42) MAOBMAOAPTGS1SDHALMNA
SCHEMBL12964467 0.87 MAOB (0.42) MAOBMAOAPTGS1SDHALMNA
SCHEMBL3325810 0.87 MAOB (0.42) MAOBMAOAPTGS1SDHALMNA
SCHEMBL5833772 0.86 MAOB (0.42) MAOBMAOAPTGS1SDHALMNA
SCHEMBL5833724 0.86 MAOB (0.42) MAOBMAOAPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200148651-A1 SUBSTITUTED PHENYLOXAZOLIDINONES FOR ANTIMICROBIAL THERAPY GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT INC (US) 2020-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200148651-A1 SUBSTITUTED PHENYLOXAZOLIDINONES FOR ANTIMICROBIAL THERAPY THPO, TBCD, OXA1L MAOB 1541/4885MAOA 2234/4885PTGS1 1413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.