Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18511520 | 0.91 | ELANE (0.58) | ELANEKMT2AATM | |
| SCHEMBL18808230 | 0.91 | ELANE (0.58) | ELANEKMT2AATM | |
| SCHEMBL19623202 | 0.90 | ELANE (0.50) | ELANEKMT2AATM | |
| SCHEMBL2123965 | 0.90 | ELANE (0.57) | ELANELMNAGAAMAPTTDP1 | |
| SCHEMBL29333589 | 0.87 | ELANE (0.50) | ELANEKMT2AATM | |
| SCHEMBL21920732 | 0.87 | ELANE (0.50) | ELANEKMT2AATM | |
| SCHEMBL20429676 | 0.85 | ELANE (0.45) | ELANEKMT2AATM | |
| SCHEMBL23919388 | 0.85 | ELANE (0.44) | ELANELMNAKMT2AATM | |
| SCHEMBL25582670 | 0.85 | ELANE (0.44) | ELANELMNAKMT2AATM | |
| SCHEMBL24377891 | 0.84 | ELANE (0.44) | ELANELMNAGAAKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023198673-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-19 | — | — | WO | disclosed |
| US-20230159825-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| EP-3666853-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2020-06-17 | — | — | EP | disclosed |
| US-10642104-B2 | Method of controlling the pretilt angle in polymer stabilised liquid crystal displays | MERCK PATENT GMBH (DE) | 2020-05-05 | — | — | US | disclosed |