Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001403 | 0.87 | MEN1 (0.58) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL22001536 | 0.85 | CYP2C19 (0.56) | KMT2AALDH1A1KDM4EMAOBHPGD | |
| SCHEMBL22001538 | 0.85 | MAOB (0.42) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL22001829 | 0.82 | MAOB (0.40) | MEN1KMT2AALDH1A1KDM4EMAOB | |
| SCHEMBL22001542 | 0.79 | MEN1 (0.61) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL13432119 | 0.75 | MAOB (0.76) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL13840825 | 0.75 | MAOB (0.76) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL17737793 | 0.74 | KMT2A (0.65) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL23239782 | 0.73 | MAOB (0.58) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL23212913 | 0.73 | MEN1 (0.71) | MEN1MAPTKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148660-A1 | COUMARIN OXIME ESTER COMPOUNDS, PREPARATION AND USE THEREOF | HUBEI GURUN TECHNOLOGY CO. LTD (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148660-A1 | COUMARIN OXIME ESTER COMPOUNDS, PREPARATION AND USE THEREOF | CBR3, POR, CYP3A4 | MEN1 3755/4885MAPT 1764/4885KMT2A 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.