Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001538 | 0.90 | MAOB (0.42) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22001553 | 0.88 | MAOB (0.41) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22001536 | 0.83 | CYP2C19 (0.56) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22001831 | 0.82 | MEN1 (0.53) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22001546 | 0.82 | MAOB (0.39) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22001539 | 0.77 | MAOB (0.43) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22058878 | 0.76 | MAOB (0.43) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22001552 | 0.71 | HSD11B1 (0.43) | MAOBALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL22001540 | 0.70 | CYP2C19 (0.58) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL24677611 | 0.70 | CES2 (0.42) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142511-B2 | Coumarin oxime ester compounds, preparation and use thereof | HUBEI GURUN TECHNOLOGY CO., LTD. (CN) | 2021-10-12 | — | — | US | disclosed |
| EP-3660008-A1 | COUMARIN OXIME ESTER COMPOUND AND PREPARATION AND USE THEREOF | Hubei Gurun Technology Co., Ltd (CN) | 2020-06-03 | — | — | EP | disclosed |
| US-20200148660-A1 | COUMARIN OXIME ESTER COMPOUNDS, PREPARATION AND USE THEREOF | HUBEI GURUN TECHNOLOGY CO. LTD (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148660-A1 | COUMARIN OXIME ESTER COMPOUNDS, PREPARATION AND USE THEREOF | CBR3, POR, CYP3A4 | MAOB 660/4885MAOA 1167/4885ALDH1A1 457/4885 |
| US-11142511-B2 | Coumarin oxime ester compounds, preparation and use thereof | CBR3, POR, CYP3A4 | MAOB 660/4885MAOA 1167/4885ALDH1A1 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.