SCHEMBL22003294

SCHEMBL22003294

CC(C)C(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCCCC[C@H](N)C(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.58
▸ NOD1 Q9Y239 9/20 0.47
▸ FOLH1 Q04609 2/20 0.38
▸ FNTA P49354 1/20 0.37
▸ FNTB P49356 1/20 0.37
▸ PGGT1B P53609 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22003293 0.90 GLP1R (0.58) GLP1RNOD1FOLH1
SCHEMBL21725212 0.87 GLP1R (0.55) GLP1RNOD1FOLH1
SCHEMBL19135682 0.86 GLP1R (0.51) GLP1RNOD1
SCHEMBL26076118 0.85 GLP1R (0.77) GLP1RNOD1
SCHEMBL25546639 0.85 GLP1R (0.54) GLP1RNOD1FOLH1
SCHEMBL24249840 0.85 GLP1R (0.68) GLP1RNOD1FOLH1
SCHEMBL21110472 0.85 GLP1R (0.68) GLP1RNOD1FOLH1
SCHEMBL19034796 0.85 GLP1R (0.68) GLP1RNOD1FOLH1
SCHEMBL1758670 0.85 GLP1R (0.68) GLP1RNOD1FOLH1
SCHEMBL24249859 0.85 GLP1R (0.68) GLP1RNOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200155639-A1 MODULATORS OF COMPLEMENT ACTIVITY UCB HOLDINGS, INC. 2020-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200155639-A1 MODULATORS OF COMPLEMENT ACTIVITY C3AR1, C1QBP, C5AR1 GLP1R 575/4885NOD1 1517/4885FOLH1 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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