Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodometomidate I-123, R- SCHEMBL4870043 | 0.88 | MAPK1 (0.74) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| Iodometomidate I-123, R- SCHEMBL4870040 | 0.88 | MAPK1 (0.74) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| Metomidate SCHEMBL4377172 | 0.87 | MAPK1 (0.97) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| Metomidate SCHEMBL491910 | 0.87 | MAPK1 (0.97) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| Metomidate SCHEMBL1845324 | 0.86 | MAPK1 (1.00) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| SCHEMBL5140230 | 0.85 | MAPK1 (0.70) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| SCHEMBL5140228 | 0.85 | MAPK1 (0.70) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| Metomidate SCHEMBL11733503 | 0.83 | MAPK1 (0.88) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| SCHEMBL11492842 | 0.83 | MAPK1 (0.67) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| SCHEMBL10623371 | 0.81 | MAPK1 (0.51) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900278-B1 | RADIOPHARMACEUTICAL PRODUCTS FOR DIAGNOSIS AND THERAPY OF ADRENAL CARCINOMA | UNIV WUERZBURG J MAXIMILIANS (DE) | 2020-05-20 | — | — | EP | disclosed |