Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.41 |
| ▸ | CKS1B | P61024 | 2/20 | 0.39 |
| ▸ | SKP1 | P63208 | 2/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21464174 | 0.85 | CRBN (0.56) | DDB1CRBNMAPTPTPN11GPR119 | |
| SCHEMBL30892104 | 0.85 | CRBN (0.56) | DDB1CRBNMAPTPTPN11GPR119 | |
| SCHEMBL20234574 | 0.85 | CRBN (0.56) | DDB1CRBNMAPTPTPN11GPR119 | |
| SCHEMBL22906700 | 0.69 | CRBN (0.45) | DDB1CRBNMAPTGPR119 | |
| SCHEMBL20234327 | 0.69 | CRBN (0.59) | DDB1CRBN | |
| SCHEMBL20046675 | 0.69 | DDB1 (0.56) | DDB1CRBNGPR119CKS1BSKP1 | |
| SCHEMBL20482058 | 0.68 | MAPT (0.55) | DDB1CRBNMAPTPTPN11GPR119 | |
| SCHEMBL24964189 | 0.68 | GPR119 (0.61) | DDB1CRBNMAPTPTPN11GPR119 | |
| SCHEMBL22725112 | 0.68 | GPR119 (0.60) | MAPTPTPN11GPR119CKS1BSKP1 | |
| SCHEMBL1447940 | 0.67 | GPR119 (0.65) | MAPTPTPN11GPR119CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155690-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155690-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | CRBN, CBL, MDM2 | DDB1 399/4885CRBN 1/4885MAPT 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.