Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18946127 | 1.00 | GLS (0.51) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL17309262 | 0.81 | GLS (0.47) | GLS | |
| SCHEMBL20373254 | 0.81 | GLS (0.47) | GLS | |
| SCHEMBL17654164 | 0.68 | GLS (1.00) | GLS | |
| SCHEMBL17654160 | 0.68 | GLS (1.00) | GLS | |
| SCHEMBL17654158 | 0.68 | GLS (1.00) | GLS | |
| SCHEMBL11584394 | 0.66 | — | — | |
| SCHEMBL24831877 | 0.63 | NPC1 (0.40) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL17664538 | 0.61 | GLS (0.61) | GLS | |
| SCHEMBL13599897 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383872-B1 | 1,3,4-THIADIAZOLE COMPOUNDS AND THEIR USE IN TREATING CANCER | CANCER RESEARCH TECH LTD (GB) | 2020-05-20 | — | — | EP | disclosed |