Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 10/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197464 | 0.92 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2199501 | 0.90 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2195134 | 0.90 | MAPK13 (0.70) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2199405 | 0.89 | MAPK14 (0.61) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL27634454 | 0.88 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2199428 | 0.88 | MAPK14 (0.60) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2200130 | 0.88 | MAPK14 (0.52) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2202412 | 0.85 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2199858 | 0.84 | MAPK14 (0.52) | MAPK13MAPK12MAPK11MAPK14RAB9A | |
| SCHEMBL2198749 | 0.83 | MAPK14 (0.54) | MAPK13MAPK12MAPK11MAPK14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658263-B9 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2011-11-09 | — | — | EP | disclosed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| EP-1658263-B1 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2010-06-02 | — | — | EP | disclosed |
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | NFKBIA, UACA, ALDH7A1 | MAPK13 1063/4885MAPK12 955/4885MAPK11 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.