Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16984291 | 0.76 | HRH3 (0.35) | HRH3CYP2D6 | |
| SCHEMBL18705140 | 0.75 | HRH3 (0.31) | HRH3 | |
| SCHEMBL14546271 | 0.73 | HRH3 (0.33) | HRH3CYP2D6 | |
| SCHEMBL18705136 | 0.73 | HRH3 (0.36) | HRH3 | |
| SCHEMBL23022406 | 0.71 | PTPN11 (0.42) | — | |
| SCHEMBL20909177 | 0.71 | PTPN11 (0.42) | — | |
| SCHEMBL20909286 | 0.71 | PTPN11 (0.42) | — | |
| SCHEMBL22520445 | 0.71 | PTPN11 (0.42) | — | |
| SCHEMBL19756436 | 0.71 | CYP2D6 (0.36) | HRH3CYP2D6 | |
| SCHEMBL19756456 | 0.71 | CYP2D6 (0.36) | HRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954244-B2 | Compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200157106-A1 | Novel Compounds and Uses Thereof | KALA BIO, Inc. | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157106-A1 | Novel Compounds and Uses Thereof | RB1, VEGFA, UACA | HRH3 2389/4885CHRM1 1386/4885CYP2D6 3557/4885 |
| US-10954244-B2 | Compounds and uses thereof | RB1, VEGFA, FLT4 | HRH3 2294/4885CHRM1 2017/4885CYP2D6 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.