Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21903812 | 0.95 | BTK (0.41) | BTKGPR119 | |
| SCHEMBL22009288 | 0.86 | BTK (0.35) | BTKGPR119OPRK1 | |
| SCHEMBL21903726 | 0.84 | BTK (0.38) | BTKGPR119 | |
| SCHEMBL21903821 | 0.82 | GPR119 (0.37) | GPR119 | |
| SCHEMBL22008945 | 0.81 | GPR119 (0.33) | BTKGPR119 | |
| SCHEMBL21965241 | 0.81 | BTK (0.36) | BTK | |
| SCHEMBL21965766 | 0.80 | BTK (0.49) | BTKEGFR | |
| SCHEMBL31684271 | 0.80 | BTK (0.49) | BTKEGFR | |
| SCHEMBL21903689 | 0.80 | BTK (0.49) | BTKEGFR | |
| SCHEMBL21903643 | 0.80 | BTK (0.46) | BTKEGFROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653626-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-05-20 | — | — | EP | disclosed |