Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31684325 | 0.90 | BTK (0.43) | BTKEGFR | |
| SCHEMBL21965240 | 0.90 | BTK (0.43) | BTKEGFR | |
| SCHEMBL22009287 | 0.89 | BTK (0.45) | BTKEGFRKITFLT3 | |
| SCHEMBL21903675 | 0.84 | BTK (0.45) | BTKEGFRKITFLT3 | |
| SCHEMBL21903750 | 0.84 | BTK (0.45) | BTKEGFRKITFLT3 | |
| SCHEMBL21966562 | 0.84 | BTK (0.45) | BTKEGFRKITFLT3 | |
| SCHEMBL31684267 | 0.84 | BTK (0.45) | BTKEGFRKITFLT3 | |
| SCHEMBL21903581 | 0.84 | BTK (0.45) | BTKEGFRKITFLT3 | |
| SCHEMBL21903605 | 0.84 | BTK (0.45) | BTKEGFRKITFLT3 | |
| SCHEMBL31684311 | 0.84 | BTK (0.45) | BTKEGFRKITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653626-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-05-20 | — | — | EP | disclosed |