Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22009032 | 0.89 | BTK (0.42) | BTKKITFLT3EGFR | |
| SCHEMBL31684267 | 0.89 | BTK (0.45) | BTKKITFLT3EGFRLCK | |
| SCHEMBL21903605 | 0.89 | BTK (0.45) | BTKKITFLT3EGFRLCK | |
| SCHEMBL21903581 | 0.89 | BTK (0.45) | BTKKITFLT3EGFRLCK | |
| SCHEMBL21966562 | 0.89 | BTK (0.45) | BTKKITFLT3EGFRLCK | |
| SCHEMBL21903750 | 0.89 | BTK (0.45) | BTKKITFLT3EGFRLCK | |
| SCHEMBL21903675 | 0.89 | BTK (0.45) | BTKKITFLT3EGFRLCK | |
| SCHEMBL31684311 | 0.89 | BTK (0.45) | BTKKITFLT3EGFRLCK | |
| SCHEMBL21903566 | 0.87 | BTK (0.44) | BTKKITFLT3EGFRLCK | |
| SCHEMBL24040170 | 0.87 | ITK (0.40) | BTKEGFRITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653626-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-05-20 | — | — | EP | disclosed |