Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 14/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 12/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.36 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20481147 | 0.99 | ITGAV (0.36) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL21832084 | 0.85 | ITGAV (0.45) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL20481005 | 0.85 | ITGAV (0.44) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL275997 | 0.84 | HRH4 (0.44) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| Hydrochloric Acid SCHEMBL20481273 | 0.82 | HRH4 (0.43) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL20481128 | 0.82 | ITGAV (0.44) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL20481003 | 0.80 | ITGAV (0.48) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL20481396 | 0.79 | KCNH2 (0.46) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL22008995 | 0.79 | KCNH2 (0.46) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL22008993 | 0.79 | KCNH2 (0.46) | ITGAVITGB6ITGB3ITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827621-B2 | Inhibitors of (α-v)(β-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| CN-110573499-B | Inhibitors of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20210276975-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC, INC. | 2021-09-09 | — | — | US | disclosed |
| US-11046669-B2 | Inhibitors of (α-v)(β-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-11040955-B2 | Inhibitors of (alpha-v)(beta-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2021-06-22 | — | — | US | disclosed |
| US-20200157075-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC, INC. | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276975-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | ITGB6, ITGA6, ITGAV | ITGAV 3/4885ITGB6 1/4885ITGB3 11/4885 |
| US-11827621-B2 | Inhibitors of (α-v)(β-6) integrin | ITGB6, ITGA6, ITGAV | ITGAV 3/4885ITGB6 1/4885ITGB3 12/4885 |
| US-20200157075-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | ITGB6, ITGA6, ITGAV | ITGAV 3/4885ITGB6 1/4885ITGB3 11/4885 |
| US-11040955-B2 | Inhibitors of (alpha-v)(beta-6) integrin | ITGB6, ITGA6, ITGAV | ITGAV 3/4885ITGB6 1/4885ITGB3 11/4885 |
| US-11046669-B2 | Inhibitors of (α-v)(β-6) integrin | ITGB6, ITGA6, ITGAV | ITGAV 3/4885ITGB6 1/4885ITGB3 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.