Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961025 | 0.81 | MEN1 (0.40) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL8960797 | 0.74 | MEN1 (0.46) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL1472536 | 0.74 | MEN1 (0.46) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL1285182 | 0.70 | TSHR (0.40) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL27879270 | 0.70 | — | — | |
| SCHEMBL6931273 | 0.70 | MEN1 (0.32) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL4823743 | 0.70 | MEN1 (0.50) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL8515493 | 0.69 | MEN1 (0.31) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL5142088 | 0.69 | TSHR (0.44) | — | |
| SCHEMBL22807004 | 0.69 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122747-B1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | NORTH & SOUTH BROTHER PHARMACY INVESTMENT CO LTD (CN) | 2020-05-20 | — | — | EP | disclosed |