Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GRM5 | P41594 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22009060 | 0.74 | NPC1 (0.50) | RAB9ANPC1MEN1KMT2AGRM5 | |
| SCHEMBL20645555 | 0.71 | MEN1 (0.52) | RAB9ANPC1MEN1KMT2AGRM5 | |
| SCHEMBL22009295 | 0.71 | HDAC2 (0.51) | RAB9ANPC1MEN1KMT2AF2 | |
| SCHEMBL22009306 | 0.71 | GRM5 (0.45) | RAB9ANPC1MEN1KMT2AGRM5 | |
| SCHEMBL3365984 | 0.70 | RAB9A (0.83) | RAB9ANPC1MEN1KMT2AGRM5 | |
| SCHEMBL29366822 | 0.70 | RAB9A (0.89) | RAB9ANPC1MEN1KMT2AF2 | |
| SCHEMBL997866 | 0.70 | RAB9A (0.89) | RAB9ANPC1MEN1KMT2AF2 | |
| SCHEMBL27548451 | 0.70 | RAB9A (0.71) | RAB9ANPC1MEN1KMT2AF2 | |
| SCHEMBL16583895 | 0.69 | RAB9A (0.86) | RAB9ANPC1MEN1KMT2AF2 | |
| SCHEMBL7189774 | 0.69 | RAB9A (0.86) | RAB9ANPC1MEN1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653626-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-05-20 | — | — | EP | disclosed |