Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18721295 | 0.88 | FGFR1 (0.33) | FGFR1SLC22A6 | |
| SCHEMBL22364090 | 0.87 | FGFR1 (0.32) | FGFR1SLC22A6 | |
| SCHEMBL22009122 | 0.87 | FGFR1 (0.32) | FGFR1SLC22A6 | |
| SCHEMBL22009997 | 0.81 | POLG (0.39) | FGFR1SLC22A6 | |
| SCHEMBL18879983 | 0.79 | FGFR1 (0.34) | FGFR1SLC22A6 | |
| SCHEMBL18721484 | 0.79 | DUT (0.33) | — | |
| SCHEMBL19590385 | 0.78 | FGFR1 (0.35) | FGFR1SLC22A6 | |
| SCHEMBL19605807 | 0.78 | FGFR1 (0.34) | FGFR1SLC22A6 | |
| SCHEMBL22009257 | 0.77 | FGFR1 (0.34) | FGFR1SLC22A6 | |
| SCHEMBL20724461 | 0.77 | FGFR1 (0.33) | FGFR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157137-A1 | 2'-CHLORO AMINOPYRIMIDINONE AND PYRIMIDINE DIONE NUCLEOSIDES | GILEAD SCIENCES, INC. | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157137-A1 | 2'-CHLORO AMINOPYRIMIDINONE AND PYRIMIDINE DIONE NUCLEOSIDES | TYMP, DPYD, TYMS | FGFR1 911/4885SLC22A6 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.