Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CSK | P41240 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22009368 | 0.84 | PRSS1 (0.45) | TPH1SLC7A5 | |
| SCHEMBL13301968 | 0.80 | SLC7A5 (0.62) | SLC7A5LNPEPERAP2 | |
| SCHEMBL16501755 | 0.80 | SLC7A5 (0.62) | SLC7A5LNPEPERAP2 | |
| SCHEMBL19733553 | 0.80 | EPHX1 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL12194007 | 0.80 | SLC7A5 (0.44) | TPH1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL26778041 | 0.80 | SLC7A5 (0.44) | TPH1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL16724760 | 0.80 | SLC7A5 (0.49) | TPH1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL12194019 | 0.79 | MME (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL19733556 | 0.79 | TP53 (0.53) | SLC7A5GRB2ANPEPERAP2PTPN1 | |
| SCHEMBL12194021 | 0.79 | TP53 (0.53) | SLC7A5GRB2ANPEPERAP2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | NGLY1, GLMN, GMPS | TPH1 1510/4885THRA 3384/4885THRB 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.