Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 4/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | TPH1 | P17752 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22009512 | 0.87 | NQO2 (0.43) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL22010463 | 0.84 | TPH1 (0.44) | TPH1SLC7A5 | |
| SCHEMBL20714851 | 0.83 | PRSS1 (0.50) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL22009360 | 0.82 | NQO2 (0.40) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL22010051 | 0.82 | L3MBTL1 (0.40) | PRSS1F2PLGTPH1SLC7A5 | |
| SCHEMBL1397441 | 0.80 | TPH1 (0.66) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL288202 | 0.80 | TPH1 (0.66) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL1064252 | 0.80 | TPH1 (0.66) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL16501755 | 0.80 | SLC7A5 (0.62) | SLC7A5 | |
| SCHEMBL12194007 | 0.80 | SLC7A5 (0.44) | TPH1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | NGLY1, GLMN, GMPS | PRSS1 2829/4885PRSS2 3045/4885PRSS3 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.