Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 4/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22010468 | 1.00 | BTK (0.47) | BTKCCNT1CDK9GPR119TNK2 | |
| SCHEMBL15803566 | 0.91 | CCNT1 (0.47) | CCNT1CDK9GPR119GRM1GRM2 | |
| SCHEMBL15803568 | 0.91 | CCNT1 (0.47) | CCNT1CDK9GPR119GRM1GRM2 | |
| SCHEMBL15803567 | 0.91 | CCNT1 (0.47) | CCNT1CDK9GPR119GRM1GRM2 | |
| SCHEMBL30161685 | 0.89 | BTK (0.52) | BTKCCNT1CDK9GPR119TNK2 | |
| SCHEMBL22010906 | 0.89 | BTK (0.52) | BTKCCNT1CDK9GPR119TNK2 | |
| SCHEMBL22010736 | 0.88 | BTK (0.45) | BTKCCNT1CDK9GPR119TNK2 | |
| SCHEMBL22010483 | 0.88 | BTK (0.45) | BTKCCNT1CDK9GPR119TNK2 | |
| SCHEMBL22010485 | 0.88 | BTK (0.45) | BTKCCNT1CDK9GPR119TNK2 | |
| SCHEMBL22010769 | 0.85 | GPR119 (0.48) | BTKCCNT1CDK9GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |