Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 4/20 | 0.71 |
| ▸ | TERT | O14746 | 1/20 | 0.70 |
| ▸ | CASP3 | P42574 | 15/20 | 0.70 |
| ▸ | PRDX1 | Q06830 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23054380 | 1.00 | NR4A1 (0.71) | NR4A1TERTCASP3PRDX1 | |
| SCHEMBL18782060 | 1.00 | NR4A1 (0.71) | NR4A1TERTCASP3PRDX1 | |
| SCHEMBL20988477 | 0.93 | HSP90AA1 (0.73) | NR4A1TERTCASP3PRDX1 | |
| SCHEMBL20988379 | 0.93 | HSP90AA1 (0.73) | NR4A1TERTCASP3PRDX1 | |
| SCHEMBL26205004 | 0.93 | NR4A1 (0.72) | NR4A1TERTCASP3PRDX1 | |
| SCHEMBL22010603 | 0.92 | NR4A1 (0.83) | NR4A1TERTCASP3 | |
| SCHEMBL18782057 | 0.92 | NR4A1 (0.83) | NR4A1TERTCASP3 | |
| SCHEMBL18781816 | 0.91 | NR4A1 (0.69) | NR4A1TERTCASP3PRDX1 | |
| SCHEMBL22010585 | 0.91 | NR4A1 (0.66) | NR4A1TERTCASP3PRDX1 | |
| SCHEMBL26208654 | 0.91 | NR4A1 (0.58) | NR4A1TERTCASP3PRDX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662218-B2 | Analogs of celastrol | ERX PHARMACEUTICALS CORPORATION | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662218-B2 | Analogs of celastrol | GIPR, GPR119, EBP | NR4A1 1945/4885TERT 3225/4885CASP3 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.