Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14704023 | 1.00 | LMNA (0.40) | LMNAALDH1A1TP53MAPK1TDP1 | |
| SCHEMBL14701613 | 0.81 | LMNA (0.40) | LMNAALDH1A1TP53MAPK1TDP1 | |
| SCHEMBL8129230 | 0.80 | LMNA (0.55) | LMNAALDH1A1TP53MAPK1TDP1 | |
| SCHEMBL27962523 | 0.76 | LMNA (0.40) | LMNAALDH1A1TP53MAPK1TDP1 | |
| SCHEMBL28806328 | 0.76 | LMNA (0.40) | LMNAALDH1A1TP53MAPK1TDP1 | |
| SCHEMBL12493182 | 0.76 | LMNA (0.40) | LMNAALDH1A1TP53MAPK1TDP1 | |
| SCHEMBL26315918 | 0.76 | LMNA (0.40) | LMNAALDH1A1TP53MAPK1TDP1 | |
| SCHEMBL5502781 | 0.76 | LMNA (0.43) | LMNAALDH1A1TP53MAPK1TDP1 | |
| SCHEMBL941113 | 0.75 | CA4 (0.43) | LMNAALDH1A1TP53CYP2C19KDM4E | |
| SCHEMBL25882988 | 0.75 | CA4 (0.43) | LMNAALDH1A1TP53CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |