SCHEMBL22011127

SCHEMBL22011127

CCCc1ccc(C#Cc2cc3oc4cc(C#Cc5ccc(OCC)cc5)c(F)cc4c3c(F)c2F)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
ACACB O00763 18/20 0.33
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8587602 0.77 ACACB (0.47) FFAR1FFAR4ACACB
SCHEMBL22011122 0.75 MAPT (0.32) FFAR1FFAR4
SCHEMBL18310400 0.74 FFAR1 (0.47) FFAR1FFAR4ACACB
SCHEMBL7859826 0.73 FFAR1 (0.55) FFAR1FFAR4ACACB
SCHEMBL7858585 0.70 FFAR1 (0.52) FFAR1FFAR4ACACB
SCHEMBL7858754 0.70 FFAR1 (0.52) FFAR1FFAR4ACACB
SCHEMBL9355338 0.70 FFAR1 (0.42) FFAR1FFAR4
SCHEMBL7859016 0.70 FFAR1 (0.47) FFAR1FFAR4ACACB
SCHEMBL10302794 0.70 FFAR4 (0.40) FFAR1FFAR4ACACBCYP11B1CYP11B2
SCHEMBL7861607 0.69 FFAR1 (0.51) FFAR1FFAR4ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 FFAR1 193/4885FFAR4 254/4885ACACB 2290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.