Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TYMS | P04818 | 5/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13383928 | 0.80 | ALDH1A1 (0.48) | CSNK2A1ALDH1A1TYMSADORA3PARP1 | |
| SCHEMBL353027 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TYMSADORA3PARP1TNKS2 | |
| SCHEMBL24157397 | 0.78 | DAO (0.39) | TYMSPARP1TNKS2LMNAHPGD | |
| SCHEMBL30212493 | 0.78 | DAO (0.39) | TYMSPARP1TNKS2LMNAHPGD | |
| SCHEMBL31569501 | 0.77 | MEN1 (0.37) | TYMSMEN1KMT2A | |
| SCHEMBL24818529 | 0.77 | MAPT (0.41) | CSNK2A1ALDH1A1TYMSADORA3PARP1 | |
| SCHEMBL9502126 | 0.76 | PARP1 (0.44) | CSNK2A1ALDH1A1TYMSADORA3PARP1 | |
| SCHEMBL6142611 | 0.76 | ALDH1A1 (0.40) | CSNK2A1ALDH1A1TYMSADORA3PARP1 | |
| SCHEMBL12020719 | 0.76 | ALDH1A1 (0.47) | CSNK2A1ALDH1A1TYMSADORA3PARP1 | |
| SCHEMBL16809167 | 0.76 | CSNK2A1 (0.39) | CSNK2A1ALDH1A1TYMSADORA3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099511-A1 | BENZIMIDAZOLE-2-METHYL-MORPHOLINE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-05-22 | — | — | WO | disclosed |