Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18997059 | 0.81 | GAA (0.42) | GAASMN1; SMN2HRH3MMP2KIF11 | |
| SCHEMBL19614569 | 0.76 | GAA (0.44) | GAASMN1; SMN2HRH3MMP2KIF11 | |
| SCHEMBL250730 | 0.76 | GAA (0.44) | GAASMN1; SMN2HRH3MMP2KIF11 | |
| SCHEMBL19614572 | 0.76 | GAA (0.44) | GAASMN1; SMN2HRH3MMP2KIF11 | |
| SCHEMBL507791 | 0.73 | GAA (0.43) | GAASMN1; SMN2HRH3MMP2KIF11 | |
| SCHEMBL105821 | 0.73 | ALDH1A3 (0.47) | GAASMN1; SMN2HRH3MMP2ALDH1A1 | |
| SCHEMBL28285633 | 0.70 | GAA (0.44) | GAASMN1; SMN2HRH3MMP2ALDH1A1 | |
| SCHEMBL20222884 | 0.70 | GAA (0.44) | GAASMN1; SMN2HRH3MMP2ALDH1A1 | |
| SCHEMBL20353279 | 0.70 | HRH3 (0.46) | GAASMN1; SMN2HRH3MMP2ALDH1A1 | |
| SCHEMBL6574277 | 0.70 | GAA (0.44) | GAASMN1; SMN2HRH3MMP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |