Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26010398 | 0.88 | NLRP3 (0.43) | NLRP3 | |
| SCHEMBL22012786 | 0.81 | NLRP3 (0.39) | NLRP3 | |
| SCHEMBL20692425 | 0.80 | NLRP3 (0.40) | NLRP3 | |
| SCHEMBL22002717 | 0.79 | — | — | |
| SCHEMBL25032751 | 0.78 | NLRP3 (0.39) | NLRP3 | |
| SCHEMBL20691979 | 0.76 | NLRP3 (0.37) | NLRP3 | |
| SCHEMBL22002944 | 0.76 | NLRP3 (0.37) | NLRP3 | |
| SCHEMBL21893648 | 0.76 | NLRP3 (0.37) | NLRP3 | |
| SCHEMBL22012214 | 0.74 | NLRP3 (0.34) | NLRP3 | |
| SCHEMBL25033693 | 0.74 | NLRP3 (0.33) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |