Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22011128 | 0.89 | SPHK1 (0.45) | SPHK1SPHK2FFAR4SSTR5 | |
| SCHEMBL22010988 | 0.81 | MPL (0.37) | FFAR4 | |
| SCHEMBL22011824 | 0.80 | SPHK1 (0.40) | SPHK1SPHK2 | |
| SCHEMBL22011219 | 0.79 | SPHK1 (0.46) | SPHK1SPHK2 | |
| SCHEMBL22011209 | 0.78 | ACE2 (0.35) | SPHK1SSTR5 | |
| SCHEMBL22011215 | 0.78 | CYP2C9 (0.36) | FFAR4KDM1A | |
| SCHEMBL22011221 | 0.77 | SPHK1 (0.34) | SPHK1SPHK2FFAR4 | |
| SCHEMBL22011124 | 0.75 | KDM1A (0.41) | SSTR5KDM1A | |
| SCHEMBL22011195 | 0.74 | SCN9A (0.39) | — | |
| SCHEMBL12733862 | 0.74 | RARB (0.39) | SPHK1SPHK2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662378-B2 | Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662378-B2 | Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device | YBX1, ZKSCAN2, RCC1 | SPHK1 2249/4885SPHK2 2044/4885FFAR4 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.