SCHEMBL22011811

SCHEMBL22011811

CCCCCC1CCC(C2CCC(c3cc4oc5cc(-c6ccc(CCC)cc6)c(F)c(F)c5c4c(F)c3F)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
S1PR3 Q99500 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22010838 0.89 RARB (0.35) RARB
SCHEMBL22011006 0.85 CYP2C9 (0.37) CYP3A4CYP2C8CYP2C9S1PR3GAA
SCHEMBL22010997 0.85 MAPT (0.33) GAAMAPT
SCHEMBL22011131 0.84 MAPT (0.31) GAAMAPT
SCHEMBL22011221 0.81 SPHK1 (0.34) MAPT
SCHEMBL22010985 0.81 FFAR4 (0.32) CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19
SCHEMBL22010813 0.81 MAPT (0.32) GAAMAPT
SCHEMBL18351428 0.80 CYP3A4 (0.33) CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19
SCHEMBL18779733 0.80 RARB (0.35) CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19
SCHEMBL22011219 0.79 SPHK1 (0.46) CYP2C9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 CYP3A4 853/4885CYP2C8 2060/4885CYP2D6 2149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.