SCHEMBL22011973

SCHEMBL22011973

CC1(C)c2ccccc2-c2cc3c4ccccc4n(-c4cccc(-c5ccccc5)c4)c3cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.40
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PGR P06401 3/20 0.34
PDE10A Q9Y233 1/20 0.34
USP2 O75604 2/20 0.32
CYP2C9 P11712 2/20 0.32
HPGD P15428 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALDH1A1 P00352 2/20 0.31
FAAH O00519 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
MGLL Q99685 1/20 0.31
CAMK2D Q13557 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24679007 0.99 ATM (0.39) ATMKDM4EL3MBTL1PGRPDE10A
SCHEMBL24886387 0.99 ATM (0.39) ATMKDM4EL3MBTL1PGRPDE10A
SCHEMBL23058895 0.98 ATM (0.38) ATMKDM4EL3MBTL1PGRPDE10A
SCHEMBL12292011 0.98 ATM (0.38) ATMKDM4EL3MBTL1PGRPDE10A
SCHEMBL803073 0.98 KDM4E (0.38) ATMKDM4EL3MBTL1PGRPDE10A
SCHEMBL15946308 0.98 KDM4E (0.38) ATMKDM4EL3MBTL1PGRPDE10A
SCHEMBL14822559 0.97 KDM4E (0.37) ATMKDM4EL3MBTL1PGRPDE10A
SCHEMBL14822512 0.97 KDM4E (0.37) ATMKDM4EL3MBTL1PGRPDE10A
SCHEMBL14822517 0.96 L3MBTL1 (0.39) ATMKDM4EL3MBTL1PGRPDE10A
SCHEMBL10001475 0.96 L3MBTL1 (0.39) ATMKDM4EL3MBTL1PGRPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020187865-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-24 WO disclosed
WO-2020099307-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-05-22 WO disclosed