Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498033 | 0.98 | RAPGEF4 (0.44) | RAPGEF4FFAR4CYP3A4HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL2202510 | 0.98 | RAPGEF4 (0.44) | RAPGEF4FFAR4CYP3A4HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL2205518 | 0.92 | RAPGEF4 (0.41) | RAPGEF4FFAR4CYP3A4HPGDALDH1A1 | |
| SCHEMBL2833625 | 0.82 | RAPGEF4 (0.42) | RAPGEF4FFAR4CYP3A4HPGDALDH1A1 | |
| SCHEMBL12355073 | 0.80 | CYP1A2 (0.51) | RAPGEF4FFAR4CYP3A4HPGDALDH1A1 | |
| SCHEMBL668651 | 0.78 | ERN1 (0.53) | CYP3A4ALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL152815 | 0.78 | RAPGEF4 (0.46) | RAPGEF4FFAR4CYP3A4HPGDALDH1A1 | |
| SCHEMBL113864 | 0.78 | RAPGEF4 (0.46) | RAPGEF4FFAR4CYP3A4HPGDALDH1A1 | |
| SCHEMBL3241201 | 0.78 | RAPGEF4 (0.46) | RAPGEF4FFAR4CYP3A4HPGDALDH1A1 | |
| SCHEMBL10498025 | 0.77 | RAPGEF4 (0.49) | RAPGEF4FFAR4CYP3A4HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018357-A1 | AROMATIC POLYSULFONE, RESIN COMPOSITION, AND METHOD FOR PRODUCING AROMATIC POLYSULFONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-01-18 | — | — | US | disclosed |
| US-20140366285-A1 | COLORING COMPOSITION FOR TEXTILE PRINTING, TEXTILE PRINTING METHOD AND FABRICS | FUJIFILM CORPORATION (JP) | 2014-12-18 | — | — | US | disclosed |
| EP-2344457-A1 | SUBSTITUTED SPIROAMINES | Grünenthal GmbH (DE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010049146-A1 | SUBSTITUTED SPIROAMINES | Grünenthal GmbH (DE) | 2010-05-06 | — | — | WO | disclosed |