Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25022494 | 0.84 | AR (0.39) | ARTSHRKDM5AMAOAMAOB | |
| SCHEMBL18999988 | 0.83 | AR (0.35) | ARTSHRKDM5AMAOAMAOB | |
| SCHEMBL13797363 | 0.83 | AR (0.45) | ARTSHRKDM5AMAOAMAOB | |
| SCHEMBL13097701 | 0.78 | AR (0.49) | AR | |
| SCHEMBL14116511 | 0.78 | AR (0.38) | ARTSHRKDM5A | |
| SCHEMBL30791049 | 0.78 | AR (0.35) | ARKDM5AMAOAMAOBIMPDH2 | |
| SCHEMBL20681127 | 0.78 | AR (0.35) | ARKDM5AMAOAMAOBIMPDH2 | |
| SCHEMBL19475486 | 0.78 | KDM4E (0.34) | ARKDM5AMAOAMAOBIMPDH2 | |
| SCHEMBL30567325 | 0.78 | KDM4E (0.34) | ARKDM5AMAOAMAOBIMPDH2 | |
| SCHEMBL21535431 | 0.76 | MAOA (0.36) | ARKDM5AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |