Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.57 |
| ▸ | FAP | Q12884 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200504 | 0.90 | DPP4 (0.57) | DPP4FAPCYP3A4FAAHCNR1 | |
| SCHEMBL2020035 | 0.90 | DPP4 (0.54) | DPP4FAP | |
| SCHEMBL2020037 | 0.90 | DPP4 (0.54) | DPP4FAP | |
| SCHEMBL2201273 | 0.87 | DPP4 (0.76) | DPP4FAPCYP3A4 | |
| SCHEMBL2024037 | 0.85 | DPP4 (0.77) | DPP4FAP | |
| SCHEMBL2024039 | 0.85 | DPP4 (0.77) | DPP4FAP | |
| SCHEMBL5426211 | 0.82 | DPP4 (0.53) | DPP4FAPCYP3A4 | |
| SCHEMBL2024583 | 0.80 | DPP4 (0.54) | DPP4 | |
| SCHEMBL2024582 | 0.80 | DPP4 (0.54) | DPP4 | |
| SCHEMBL2181463 | 0.79 | DPP4 (0.61) | DPP4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791701-A | 3- (3-aminopiperidin-1-yl) -5-oxo-1, 2, 4-triazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors | CHINA SHANGHAI FOCHON PHARMACEUTICAL CO LTD | 2012-11-21 | — | — | CN | disclosed |
| EP-2521721-A1 | 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS | Shanghai Fochon Pharmaceutical Co. Ltd (CN) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011079778-A1 | 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS | CHINA SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2011-07-07 | — | — | WO | disclosed |