Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19507077 | 0.86 | TSHR (0.32) | TSHRUSP2ALDH1A1GAAPKM | |
| SCHEMBL6280677 | 0.83 | PDE2A (0.32) | — | |
| SCHEMBL30567321 | 0.83 | PDE2A (0.32) | — | |
| SCHEMBL26860328 | 0.78 | TSHR (0.38) | TSHRRORC | |
| SCHEMBL28877103 | 0.77 | TSHR (0.41) | TSHRUSP2ALDH1A1GAAPKM | |
| SCHEMBL24978531 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL13778071 | 0.74 | TSHR (0.47) | TSHRHPGDRORC | |
| SCHEMBL10341230 | 0.73 | TSHR (0.37) | TSHRUSP2ALDH1A1GAAPKM | |
| SCHEMBL19629265 | 0.71 | TSHR (0.42) | TSHRRORC | |
| SCHEMBL20149147 | 0.70 | TSHR (0.38) | TSHRUSP2ALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |