Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280677 | 1.00 | PDE2A (0.32) | PDE2AANPEPDPP4 | |
| SCHEMBL22012652 | 0.83 | TSHR (0.36) | — | |
| SCHEMBL19507077 | 0.83 | TSHR (0.32) | — | |
| SCHEMBL15082620 | 0.79 | ANPEP (0.32) | PDE2AANPEPDPP4 | |
| SCHEMBL6751624 | 0.77 | LMNA (0.31) | — | |
| SCHEMBL17190308 | 0.77 | ANPEP (0.35) | PDE2AANPEPDPP4 | |
| SCHEMBL19505690 | 0.76 | POLB (0.34) | — | |
| SCHEMBL22014779 | 0.76 | LMNA (0.34) | ANPEPDPP4 | |
| SCHEMBL9879909 | 0.75 | GABRA1 (0.39) | — | |
| SCHEMBL12678215 | 0.75 | ACHE (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117209447-A | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117143042-A | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-111094243-B | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2023-09-05 | — | — | CN | disclosed |