Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20438453 | 0.91 | BLM (0.57) | BLMPMP22HSD17B10KDM4EMEN1 | |
| SCHEMBL22013281 | 0.84 | BLM (0.50) | BLMPMP22HSD17B10KDM4EMEN1 | |
| SCHEMBL24378680 | 0.75 | BLM (0.41) | BLMPMP22HSD17B10KDM4EMEN1 | |
| SCHEMBL19543043 | 0.75 | KDM4E (0.35) | BLMPMP22HSD17B10KDM4EKMT2A | |
| SCHEMBL20438445 | 0.74 | TDP1 (0.46) | BLMPMP22HSD17B10KDM4E | |
| SCHEMBL20438334 | 0.74 | KDM4E (0.36) | BLMPMP22HSD17B10KDM4EKMT2A | |
| SCHEMBL19543431 | 0.72 | TDP1 (0.48) | BLMPMP22HSD17B10KDM4E | |
| SCHEMBL19546729 | 0.71 | BLM (0.35) | BLMPMP22HSD17B10KDM4E | |
| SCHEMBL20438486 | 0.71 | BLM (0.40) | BLMPMP22HSD17B10 | |
| SCHEMBL17281789 | 0.70 | CA12 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, COG8 | BLM 3948/4885PMP22 4108/4885HSD17B10 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.