Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670395 | 0.82 | CA2 (0.42) | CA2 | |
| SCHEMBL21963164 | 0.80 | CA2 (0.50) | CA2 | |
| SCHEMBL7145362 | 0.80 | CA2 (0.50) | CA2CA12CA1CA9 | |
| SCHEMBL9829759 | 0.77 | CA2 (0.66) | CA2 | |
| SCHEMBL22012875 | 0.76 | CA2 (0.59) | CA2 | |
| SCHEMBL9393039 | 0.76 | CA2 (0.48) | CA2 | |
| SCHEMBL10369923 | 0.74 | CA2 (0.69) | CA2 | |
| SCHEMBL24670388 | 0.74 | CA2 (0.50) | CA2 | |
| SCHEMBL2008068 | 0.74 | CA2 (0.52) | CA2CA12CA1CA9 | |
| SCHEMBL10391021 | 0.72 | CA2 (0.60) | CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |