Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20692049 | 0.90 | NLRP3 (0.35) | NLRP3 | |
| SCHEMBL20692358 | 0.87 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL26007201 | 0.87 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL23482180 | 0.87 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL21810626 | 0.76 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL21893228 | 0.76 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL21892955 | 0.76 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL21892926 | 0.75 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL21893745 | 0.75 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL25034217 | 0.75 | NLRP3 (0.40) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |