Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.51 |
| ▸ | CYP2E1 | P05181 | 6/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 6/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17742733 | 0.84 | EGLN1 (0.64) | EGLN1CYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL4806950 | 0.84 | EGLN1 (0.67) | EGLN1CYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL7153789 | 0.82 | EGLN1 (0.62) | EGLN1CYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL4651345 | 0.80 | EGLN1 (0.60) | EGLN1CYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL9377435 | 0.76 | GABRA1 (0.46) | ALDH1A1HPGD | |
| SCHEMBL11989040 | 0.75 | AURKA (0.54) | CYP1A2CYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL4310717 | 0.75 | EGLN1 (1.00) | EGLN1CYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL7796362 | 0.75 | EGLN1 (0.57) | EGLN1CYP1A2CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL6978538 | 0.74 | KDM4E (0.58) | CYP1A2CYP2E1CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL24450250 | 0.74 | FLT3 (0.63) | KDM4EMEN1KMT2AMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662183-B2 | Inhibitors of myocardin-related transcription factor and serum response factor (MRTF/SRF)-mediated gene transcription and methods for use of the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662183-B2 | Inhibitors of myocardin-related transcription factor and serum response factor (MRTF/SRF)-mediated gene transcription and methods for use of the same | SREBF1, SREBF2, BPTF | EGLN1 2340/4885CYP1A2 3556/4885CYP2E1 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.