Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13392941 | 1.00 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13015647 | 0.84 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL10171235 | 0.81 | DPP4 (0.30) | — | |
| SCHEMBL13393272 | 0.80 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3777235 | 0.80 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL3777234 | 0.80 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL13842716 | 0.78 | POLB (0.33) | ALDH1A1 | |
| SCHEMBL8239122 | 0.78 | CYP2D6 (0.32) | ALDH1A1 | |
| SCHEMBL18254443 | 0.76 | TP53 (0.42) | ALDH1A1 | |
| SCHEMBL18254449 | 0.76 | TP53 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021098745-A1 | PREPARATION AND APPLICATION OF A CLASS OF PROTEIN RECEPTOR KINASE INHIBITORS | 上海轶诺药业有限公司 | 2021-05-27 | — | — | WO | disclosed |
| WO-2020098723-A1 | SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR | 上海轶诺药业有限公司 | 2020-05-22 | — | — | WO | disclosed |
| WO-2020098720-A1 | FIVE-AND-SIX-MEMBERED HETEROCYCLIC COMPOUND AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITOR | 上海轶诺药业有限公司 | 2020-05-22 | — | — | WO | disclosed |