Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11966962 | 0.91 | CA12 (0.74) | CA12MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4896484 | 0.87 | CA12 (0.84) | CA12MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14163515 | 0.87 | CA12 (0.84) | CA12MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4896487 | 0.87 | CA12 (0.84) | CA12MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9876664 | 0.83 | CA12 (0.67) | CA12MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL379472 | 0.81 | CA12 (0.74) | CA12MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL379471 | 0.81 | CA12 (0.74) | CA12MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7316721 | 0.76 | CA12 (0.49) | CA12KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7316716 | 0.76 | CA12 (0.49) | CA12KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL9112827 | 0.75 | CA12 (0.65) | CA12MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099596-A1 | NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 | UNIVERSITE DE ROUEN NORMANDIE (FR) | 2020-05-22 | — | — | WO | disclosed |