Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316721 | 1.00 | CA12 (0.49) | CA12CA2CA9ALDH1A1KDM4E | |
| SCHEMBL6090307 | 0.80 | CA12 (0.50) | CA12CA2CA9ALDH1A1KDM4E | |
| SCHEMBL6090311 | 0.80 | CA12 (0.50) | CA12CA2CA9ALDH1A1KDM4E | |
| SCHEMBL17660178 | 0.79 | CA12 (0.79) | CA12CA2CA9ALDH1A1KDM4E | |
| SCHEMBL348172 | 0.79 | CA12 (0.79) | CA12CA2CA9ALDH1A1KDM4E | |
| SCHEMBL13660695 | 0.79 | CA12 (0.49) | CA12CA2CA9ALDH1A1KDM4E | |
| SCHEMBL2387841 | 0.79 | CA12 (0.49) | CA12CA2CA9ALDH1A1KDM4E | |
| SCHEMBL6090480 | 0.79 | CA12 (0.49) | CA12CA2CA9ALDH1A1KDM4E | |
| SCHEMBL348171 | 0.79 | CA12 (0.79) | CA12CA2CA9ALDH1A1KDM4E | |
| SCHEMBL27751806 | 0.79 | RAB9A (0.50) | CA12CA2CA9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876255-A | CARDIOVASCULAR | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| EP-0287866-A1 | Substituted 1,4-dihydropyridines, method for their preparation and their use | BAYER AG (DE) | 1988-10-26 | — | — | EP | disclosed |