SCHEMBL22013478

SCHEMBL22013478

CNCCNC(=O)CSC(C)C

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.39
SLC6A3 Q01959 2/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31
SLC6A4 P31645 1/20 0.31
KISS1R Q969F8 1/20 0.31
MAPT P10636 1/20 0.30
USP2 O75604 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23475955 0.92 ALDH1A1 (0.45) MAPK1ALDH1A1MEN1KMT2AGAA
SCHEMBL23475969 0.86 MAPK1 (0.41) MAPK1ALDH1A1MEN1KMT2AGAA
SCHEMBL22013330 0.84 MAPK1 (0.44) MAPK1ALDH1A1TSHR
SCHEMBL23475934 0.84 MAPK1 (0.40) MAPK1ALDH1A1MEN1KMT2AGAA
SCHEMBL23475937 0.83 KMT2A (0.48) MAPK1ALDH1A1MEN1KMT2A
SCHEMBL23475972 0.82 ALDH1A1 (0.46) MAPK1ALDH1A1MEN1KMT2A
SCHEMBL22898309 0.82 MCL1 (0.44) MAPK1ALDH1A1MEN1KMT2AGAA
SCHEMBL25067184 0.82 ALDH1A1 (0.46) MAPK1ALDH1A1MEN1KMT2A
SCHEMBL23475956 0.82 ALDH1A1 (0.46) MAPK1ALDH1A1MEN1KMT2A
SCHEMBL21074913 0.80 GAA (0.47) MAPK1ALDH1A1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11220523-B2 Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein UNIVERSITÄT BASEL (CH) 2022-01-11 US disclosed
US-20210061838-A1 CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN UNIVERSITAET BASEL (CH) 2021-03-04 US disclosed
US-10662212-B2 Carbohydrate ligands that bind to IGM antibodies against myelin-associated glycoprotein UNIVERSITAT BASEL (CH) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11220523-B2 Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein MAG, PMP22, SIGLEC7 MAPK1 458/4885ALDH1A1 3342/4885SLC6A3 3508/4885
US-10662212-B2 Carbohydrate ligands that bind to IGM antibodies against myelin-associated glycoprotein MAG, PMP22, SIGLEC7 MAPK1 460/4885ALDH1A1 3216/4885SLC6A3 3460/4885
US-20210061838-A1 CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN MAG, PMP22, SIGLEC7 MAPK1 458/4885ALDH1A1 3342/4885SLC6A3 3508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.