SCHEMBL22013737

SCHEMBL22013737

COC(=O)C1O[C@@H](OC2C(OCc3ccccc3)[C@H](Oc3ccc(CCN=[N+]=[N-])cc3)OC(COCc3ccccc3)[C@@H]2OC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C(OC(=O)c2ccccc2)[C@@H]1OC(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FGF2 P09038 1/20 0.43
▸ MDK P21741 1/20 0.43
▸ NT5E P21589 1/20 0.42
▸ PTPN1 P18031 14/20 0.39
▸ PTPN2 P17706 4/20 0.38
▸ PTPN11 Q06124 3/20 0.38
▸ PTPN6 P29350 2/20 0.38
▸ LGALS3 P17931 1/20 0.38
▸ GJB2 P29033 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17087719 0.90 FGF2 (0.37) FGF2MDKNT5EPTPN1PTPN2
SCHEMBL20243571 0.88 LGALS3 (0.38) FGF2MDKNT5EPTPN1PTPN2
SCHEMBL24059832 0.88 LGALS3 (0.38) FGF2MDKNT5EPTPN1PTPN2
SCHEMBL22013736 0.84 NT5E (0.47) NT5EPTPN1PTPN2PTPN11PTPN6
SCHEMBL24059833 0.84 NT5E (0.47) NT5EPTPN1PTPN2PTPN11PTPN6
SCHEMBL18394464 0.84 NT5E (0.47) NT5EPTPN1PTPN2PTPN11PTPN6
SCHEMBL18412646 0.83 PTPN1 (0.36) FGF2MDKNT5EPTPN1PTPN2
SCHEMBL18412656 0.82 LGALS3 (0.37) FGF2MDKNT5EPTPN1PTPN2
SCHEMBL13008540 0.78 FGF2 (0.44) FGF2MDKNT5EPTPN1PTPN2
SCHEMBL18412655 0.78 FGF2 (0.36) FGF2MDKNT5EPTPN1PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662212-B2 Carbohydrate ligands that bind to IGM antibodies against myelin-associated glycoprotein UNIVERSITAT BASEL (CH) 2020-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662212-B2 Carbohydrate ligands that bind to IGM antibodies against myelin-associated glycoprotein MAG, PMP22, SIGLEC7 FGF2 1865/4885MDK 51/4885NT5E 1622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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