Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.53 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.50 |
| ▸ | ITGAL | P20701 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | ADK | P55263 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20540332 | 0.87 | PIK3CD (0.64) | PIK3CDAHRMAPK14PIK3CBPIK3CG | |
| SCHEMBL3291196 | 0.84 | ALDH1A1 (0.53) | ASH1LKDM4E | |
| SCHEMBL6322730 | 0.78 | PIK3CD (0.61) | PIK3CDAHRMAPK14PIK3CBPIK3CG | |
| SCHEMBL6330094 | 0.78 | MAPK14 (0.53) | PIK3CDAHRTRPA1MAPK14PIK3CB | |
| SCHEMBL6321487 | 0.78 | RHEB (0.57) | PIK3CDAHRMAPK14PIK3CBASH1L | |
| SCHEMBL27504679 | 0.78 | PIK3CD (0.51) | PIK3CDAHRCA1CA2CA4 | |
| SCHEMBL29712113 | 0.78 | PIK3CD (0.70) | PIK3CDAHRMAPK14PIK3CBPIK3CG | |
| SCHEMBL2193011 | 0.78 | PIK3CD (0.70) | PIK3CDAHRMAPK14PIK3CBPIK3CG | |
| SCHEMBL28534545 | 0.78 | PARP1 (0.45) | AHRTRPA1CA1CA2ITGB2 | |
| SCHEMBL25302086 | 0.78 | ALDH1A1 (0.59) | CA1CA2KDM4EALPLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113373-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020113759-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020098630-A1 | ANIMAL MODELS, SCREENING METHODS, AND TREATMENT METHODS FOR INTRAOCULAR DISEASES OR DISORDERS | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-05-22 | — | — | WO | disclosed |