Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069598 | 0.81 | KDM4E (0.58) | ALDH1A1HSD17B10MAPTKDM4EMEN1 | |
| SCHEMBL28037999 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HSD17B10MAPTKDM4EMEN1 | |
| SCHEMBL27920219 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HSD17B10MAPTKDM4EMEN1 | |
| SCHEMBL12637458 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4ENAMPT | |
| SCHEMBL27451256 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EPOLBKMT2A | |
| SCHEMBL27877183 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4ENAMPT | |
| SCHEMBL25523906 | 0.74 | MAPT (0.50) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| SCHEMBL926871 | 0.73 | NAMPT (0.46) | ALDH1A1HSD17B10KDM4ENAMPT | |
| SCHEMBL12637452 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HSD17B10MAPTKDM4ENAMPT | |
| SCHEMBL25462074 | 0.72 | KDM4E (0.39) | ALDH1A1HSD17B10MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113373-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020113759-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020098630-A1 | ANIMAL MODELS, SCREENING METHODS, AND TREATMENT METHODS FOR INTRAOCULAR DISEASES OR DISORDERS | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-05-22 | — | — | WO | disclosed |