Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 18/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22013614 | 0.78 | MAP4K4 (0.47) | MAP4K4PDE10A | |
| SCHEMBL23836955 | 0.78 | MAP4K4 (0.53) | MAP4K4PDE10A | |
| SCHEMBL22013122 | 0.78 | MAP4K4 (0.53) | MAP4K4PDE10A | |
| SCHEMBL23837028 | 0.78 | MAP4K4 (0.47) | MAP4K4PDE10A | |
| SCHEMBL22013660 | 0.72 | MAP4K4 (0.42) | MAP4K4PDE10ABRAF | |
| SCHEMBL24200709 | 0.72 | NTRK1 (0.43) | — | |
| SCHEMBL23836944 | 0.71 | MAP4K4 (0.52) | MAP4K4PDE10A | |
| SCHEMBL23837046 | 0.70 | MAP4K4 (0.56) | MAP4K4 | |
| SCHEMBL23837047 | 0.70 | MAP4K4 (0.56) | MAP4K4 | |
| SCHEMBL22013665 | 0.70 | MAP4K4 (0.56) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882247-A1 | SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR | Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) | 2021-09-22 | — | — | EP | disclosed |
| WO-2020098723-A1 | SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR | 上海轶诺药业有限公司 | 2020-05-22 | — | — | WO | disclosed |