Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 16/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23837028 | 1.00 | MAP4K4 (0.47) | MAP4K4PDE10AP2RX7 | |
| SCHEMBL23836955 | 0.84 | MAP4K4 (0.53) | MAP4K4PDE10A | |
| SCHEMBL22013122 | 0.84 | MAP4K4 (0.53) | MAP4K4PDE10A | |
| SCHEMBL22013429 | 0.81 | MAP4K4 (0.56) | MAP4K4 | |
| SCHEMBL23837046 | 0.81 | MAP4K4 (0.56) | MAP4K4 | |
| SCHEMBL22013253 | 0.81 | MAP4K4 (0.45) | MAP4K4PDE10AP2RX7 | |
| SCHEMBL22013226 | 0.80 | MAP4K4 (0.54) | MAP4K4 | |
| SCHEMBL23836993 | 0.78 | MAP4K4 (0.42) | MAP4K4P2RX7 | |
| SCHEMBL22013660 | 0.78 | MAP4K4 (0.42) | MAP4K4PDE10AP2RX7 | |
| SCHEMBL22014130 | 0.78 | MAP4K4 (0.42) | MAP4K4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098723-A1 | SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR | 上海轶诺药业有限公司 | 2020-05-22 | — | — | WO | disclosed |