Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104241 | 0.86 | KMT2A (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2EPHX1 | |
| SCHEMBL25654193 | 0.80 | MEN1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL24330217 | 0.79 | GAA (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL18649603 | 0.79 | KDM4E (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2CASP2 | |
| SCHEMBL18649601 | 0.79 | KMT2A (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2CASP2 | |
| SCHEMBL8050436 | 0.79 | MEN1 (0.64) | MEN1KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL19465893 | 0.78 | POLB (0.36) | MEN1KMT2A | |
| SCHEMBL23475971 | 0.78 | KMT2A (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL24118140 | 0.77 | SMN1; SMN2 (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL21208110 | 0.77 | KMT2A (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102243-A2 | IN-FLOW PHOTOOXYGENATION OF AMINOTHIENOPYRIDINONES GENERATES NOVEL PTP4A3 PHOSPHATASE INHIBITORS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2020-05-22 | — | — | WO | disclosed |